半负荷量替罗非班对急性STEMI患者急诊PCI术治疗后心肌生化标志物的影响分析

The influence of half load Tirofiban on myocardial biochemical marker of patients with acute STEMI after emergency PCI

摘要

: 任务 讨论半爆炸力替罗非班对严重的ST段抬高型心肌梗死(STEMI)病人急诊经皮冠状血管沾手(PCI)措施后心肌生化指定而尚未上任的物的压紧.办法 拔取2012年11月至2015年11月承担急诊PCI措施的STEMI病人218例为默想不赞成,地基术前条件消耗替罗非班措施。,108例)与对照组(未消耗替罗非班110例).分开在两组病人手术前及术后48 H为病人。

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Abstract:

Objective To explore the influence of half load Tirofiban on myocardial biochemical marker of emergency PCI patients with acute STEMI.Methods From November 2012 to November 2015, 218 cases of STEMI patients received emergency PCI treatment were selected as the research object, according to the use of tirofiban before surgery, they were divided into treatment group (108 cases of 替罗非班 and control group (110 例), respectively.Troponin creatine kinase, amino terminal B type natriuretic peptide (NT-proBNP) levels before and after operation of 48 h were measured, and the cardiac function indexes of two groups in 24h and 60D after operation were evaluated.Adverse cardiac events (锏) and the incidence of bleeding complications were observed during hospitalization and postoperative 90 d.Results Compared with before surgery, troponin, creatine kinase, NT-pro-BNP levels in postoperative 48h treatment group and the control group were significantly increased, 和 indexes in the control group at 48h after operation were significantly higher (P<);LVESV and LVEDV within 24h and postoperative 60Din treatment group were lower than those of the control group, and LVEF was higher than that of the control group (P<).The treatment group occurred MACE 5 cases (), 2 cases of bleeding complications occurred in the control group (), MACE12 ( 例), 1 cases of bleeding complications (0.9 1%), the incidence of MACE in the treatment group was significantly lower than that in the control group (P<), and the incidence of bleeding complications in the two groups was not significantly different (P>).Conclusion Half dose tirofiban can effectively reduce the level of myocardial biochemical markers in patients with acute STEMI after emergency PCI, and can improve the short-term prognosis, which is worthy of clinical 消耗。

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