半负荷量替罗非班对急性STEMI患者急诊PCI术治疗后心肌生化标志物的影响分析

The influence of half load Tirofiban on myocardial biochemical marker of patients with acute STEMI after emergency PCI

摘要

: 意愿坚决的 根究半生产能力替罗非班对敏锐的ST段抬高型心肌梗死(STEMI)有耐性的急诊经皮冠状血管沾手(PCI)补救后心肌生化选出而尚未上任的物的挤入.方式 拔取2012年11月至2015年11月接纳急诊PCI补救的STEMI有耐性的218例为探讨反对,战场术前设想器械替罗非班补救。,108例)与对照组(未器械替罗非班110例).辨别出在两组有耐性的手术前及术后48 H为有耐性的。

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Abstract:

Objective To explore the influence of half load Tirofiban on myocardial biochemical marker of emergency PCI patients with acute STEMI.Methods From November 2012 to November 2015, 218 cases of STEMI patients received emergency PCI treatment were selected as the research object, according to the use of tirofiban before surgery, they were divided into treatment group (108 cases of 替罗非班 and control group (110 事例), respectively.Troponin creatine kinase, amino terminal B type natriuretic peptide (NT-proBNP) levels before and after operation of 48 h were measured, and the cardiac function indexes of two groups in 24h and 60D after operation were evaluated.Adverse cardiac events (锏) and the incidence of bleeding complications were observed during hospitalization and postoperative 90 d.Results Compared with before surgery, troponin, creatine kinase, NT-pro-BNP levels in postoperative 48h treatment group and the control group were significantly increased, 和 indexes in the control group at 48h after operation were significantly higher (P<);LVESV and LVEDV within 24h and postoperative 60Din treatment group were lower than those of the control group, and LVEF was higher than that of the control group (P<).The treatment group occurred MACE 5 cases (), 2 cases of bleeding complications occurred in the control group (), MACE12 ( 事例), 1 cases of bleeding complications (0.9 1%), the incidence of MACE in the treatment group was significantly lower than that in the control group (P<), and the incidence of bleeding complications in the two groups was not significantly different (P>).Conclusion Half dose tirofiban can effectively reduce the level of myocardial biochemical markers in patients with acute STEMI after emergency PCI, and can improve the short-term prognosis, which is worthy of clinical 器械。

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